Histopathological Changes in Canine Demodicosis

Immunology and pathogenesis of canine demodicosis.

Demodex mites colonized the hair follicles and sebaceous glands of mammals millions of years ago and have remained relatively unchanged in this protected ecologic niche since then. The host immune system detects and tolerates their presence. Toll-like receptor-2 of keratinocytes has been demonstrated to recognize mite chitin and to elicit an innate immune response. The subsequent acquired immun...

Practical and update management of canine demodicosis

Canine demodicosis is a common parasitic skin disease in dogs. It can be classified into 2 types based on distribution of lesion; localized and generalized demodicosis. Localized demodicois was reported to be usually spontaneous remission, therefore, no treatment is needed. Generalized demodicosis, on the other hand, cannot heal spontaneously so miticidal therapy should be prescribed. However, ...

What Is New about Canine Demodicosis

An Update on Therapeutic Management of Canine Demodicosis

Canine demodicosis is a common noncontagious parasitic dermatosis caused by different spp of Demodex mites including Demodex canis, Demodex injai and D. cornei. Generalized demodicosis can be one of the most frustrating skin diseases, one will ever treat. Conventional and newer miticidal therapies are available to veterinarian to treat this frustrating skin disease. All recognized Demodex mites...

A retrospective evaluation of efficiency in therapy for generalized canine demodicosis

During the period 1993-2003, generalized demodicosis was diagnosed in 517 dogs. Two hundred and sixty-five (51.2%) dogs were cured with amitraz 0.025% solution, 199 (38.5%) were cured after amitraz 0.05% solution was introduced, and in 53 dogs (10.3%) mites were amitraz resistant. Among amitraz-resistent dogs, 48 were introduced to 600 μg kg-1 oral ivermectin protocol, and 45 (89.6%) of this nu...